BDBM50606738 CHEMBL5218590::US11731973, Example 6
SMILES CCC(C)(C)Cn1nc(-c2ccc3oc(NC(C)=O)nc3c2)c2c(N)nc(N)nc12
InChI Key InChIKey=XGKILEKRCLGRHL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50606738
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Homo sapiens)
University of Hradec Kralove
Curated by ChEMBL
University of Hradec Kralove
Curated by ChEMBL
Affinity DataIC50: 5.90nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetTarget of rapamycin complex subunit LST8(Homo sapiens)
University of Hradec Kralove
Curated by ChEMBL
University of Hradec Kralove
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of mTORC1 in human A-431 cells assessed as phosphorylated S6RP level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair