BDBM50085041 2-(4-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy)phenoxy)acetic acid::CHEMBL153057::L-165041::L165041::{4-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-propoxy]-phenoxy}-acetic acid(L-165041)::{4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy}acetic acid

SMILES CCCc1c(O)c(ccc1OCCCOc1ccc(OCC(O)=O)cc1)C(C)=O

InChI Key InChIKey=HBBVCKCCQCQCTJ-UHFFFAOYSA-N

Data  1 IC50  2 Kd  20 EC50  1 Koff  1 ITC

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50085041   

TargetFatty acid-binding protein, intestinal(Homo sapiens (Human))
Monash University

LigandPNGBDBM50085041(2-(4-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propox...)
Affinity DataKd:  7.20E+3nMpH: 8.0 T: 2°CAssay Description:ITC experiments were carried out using an iTC200 microcalorimeter (MicroCal) with coin shaped sample cell (200 μL) at 37 C with stirring at 1000...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50085041(2-(4-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propox...)
Affinity DataKd:  76nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair

Activity Spreadsheet -- ITC Data from BindingDB

Found 1 hit for monomerid = 50085041   

CellIntestinal fatty acid-binding protein (hIFABP)(Homo sapiens (Human))
Monash University

SyringePNGBDBM50085041(2-(4-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propox...)
ITC DataΔG°: -7.31kcal/mole −TΔS°: 2.91kcal/mole ΔH°: -10.2kcal/mole logk: 1.42E+5
pH: 8.0 T: 37.00°C 
In DepthDetails ArticlePubMed