BDBM12074 (2R)-2-{[4-(4-bromophenyl)benzene]sulfonamido}-3-methylbutanoic acid::CHEMBL42420::alpha-arylsulfonylamino carboxylate 2R

SMILES CC(C)[C@@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(Br)cc1)C(O)=O

InChI Key InChIKey=GJOCABIDMCKCEG-MRXNPFEDSA-N

Data  1 KI  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12074   

TargetStromelysin-1(Homo sapiens (Human))
Istituto Di Cristallografia

LigandPNGBDBM12074((2R)-2-{[4-(4-bromophenyl)benzene]sulfonamido}-3-m...)
Affinity DataKi:  54.9nM ΔG°:  -9.90kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition of the matrix metalloproteinases MMP-2, MMP-3, and MMP-8 has been determined by continuously monitoring the hydrolysis of the fluorescent ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed