BDBM12704 1-(3-amino-1,2-benzoxazol-5-yl)-6-[2-fluoro-4-(2-{[(3R)-3-hydroxypyrrolidin-1-yl]methyl}phenyl)phenyl]-3-methyl-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-7-one::BMS-740808 Analogue 12d
SMILES Cc1nn(c2c1CCN(C2=O)c1ccc(cc1F)-c1ccccc1CN1CC[C@@H](O)C1)-c1ccc2onc(N)c2c1
InChI Key InChIKey=JNQXDDWCPSDRRR-JOCHJYFZSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 12704
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Bristol-Myers Squibb Pharmaceutical Research Institute
Affinity DataKi: 0.340nM ΔG°: -12.8kcal/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair