BDBM50118750 2-(Oxalyl-amino)-6-phenethyl-4,5,6,7-tetrahydro-thieno[2,3-c]pyridine-3-carboxylic acid::CHEMBL140120
SMILES OC(=O)C(=O)Nc1sc2CN(CCc3ccccc3)CCc2c1C(O)=O
InChI Key InChIKey=ZIMJSFGMHLCHIV-UHFFFAOYSA-N
Data 9 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50118750
Affinity DataKi: 270nMAssay Description:Inhibition of PTP1B (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 270nMpH: 5.5Assay Description:Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.More data for this Ligand-Target Pair
Affinity DataKi: 270nMpH: 5.5Assay Description:Inhibition of human recombinant PTP1B (1 to 321 residues) catalytic domain expressed in Escherichia coli BL21 (DE3) cells using p-nitrophenyl phospha...More data for this Ligand-Target Pair
Affinity DataKi: 3.20E+3nMAssay Description:Inhibition of human recombinant Protein-tyrosine phosphatase 1B.More data for this Ligand-Target Pair
Affinity DataKi: 3.20E+3nMAssay Description:Inhibition of human recombinant Protein-tyrosine phosphatase 1B.More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 7.20E+3nMpH: 7.0Assay Description:Inhibition of recombinant TCPTP (unknown origin) at pH 7More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Novo Nordisk
Curated by ChEMBL
Novo Nordisk
Curated by ChEMBL
Affinity DataKi: 1.40E+6nMpH: 7.0Assay Description:Inhibitory effect against human CD45 tyrosine phosphatase using p-nitrophenyl phosphate substrate at a pH 7.0More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Novo Nordisk
Curated by ChEMBL
Novo Nordisk
Curated by ChEMBL
Affinity DataKi: 2.10E+6nMpH: 7.0Assay Description:Inhibitory effect against human Protein-tyrosine phosphatase alpha (PTPalpha) using p-nitrophenyl phosphate substrate at a pH 7.0More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Novo Nordisk
Curated by ChEMBL
Novo Nordisk
Curated by ChEMBL
Affinity DataKi: 2.10E+6nMpH: 7.0Assay Description:Inhibitory effect against human Protein-tyrosine phosphatase Lar using p-nitrophenyl phosphate substrate at a pH 7.0More data for this Ligand-Target Pair