BDBM50138699 5-(3-(benzyloxy)-4-methoxybenzyl)pyrimidine-2,4-diamine::5-(3-Benzyloxy-4-methoxy-benzyl)-pyrimidine-2,4-diamine::CHEMBL291931
SMILES COc1ccc(Cc2cnc(N)nc2N)cc1OCc1ccccc1
InChI Key InChIKey=XARRNBRDTOCYPU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50138699
Affinity DataKi: 0.0977nMAssay Description:Apparent inhibitory (log 1/Ki) activity against Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
National Center For Genetic Engineering and Biotechnology At Thailand
Curated by ChEMBL
National Center For Genetic Engineering and Biotechnology At Thailand
Curated by ChEMBL
Affinity DataKi: 7.20nMAssay Description:Inhibitory activity against wild-type dihydrofolate reductase (S108N DHFR)More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Salmonella enterica subsp. enterica serovar Typhi)
Pomona College
Curated by ChEMBL
Pomona College
Curated by ChEMBL
Affinity DataKi: 22nMAssay Description:Inhibitory activity against Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 123nMAssay Description:Inhibitory activity against Lactobacillus casei dihydrofolate reductaseMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
National Center For Genetic Engineering and Biotechnology At Thailand
Curated by ChEMBL
National Center For Genetic Engineering and Biotechnology At Thailand
Curated by ChEMBL
Affinity DataKi: 143nMAssay Description:Inhibitory activity against double mutant dihydrofolate reductase (C59R+S108N DHFR)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
National Center For Genetic Engineering and Biotechnology At Thailand
Curated by ChEMBL
National Center For Genetic Engineering and Biotechnology At Thailand
Curated by ChEMBL
Affinity DataKi: 630nMAssay Description:Inhibitory activity against triple mutant dihydrofolate reductase (C59R S108 NI164L DHFR)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
National Center For Genetic Engineering and Biotechnology At Thailand
Curated by ChEMBL
National Center For Genetic Engineering and Biotechnology At Thailand
Curated by ChEMBL
Affinity DataKi: 1.13E+3nMAssay Description:Inhibitory activity against quadruple mutant dihydrofolate reductase (N51I C59R S108N I164L DHFR)More data for this Ligand-Target Pair
Affinity DataKi: 1.82E+4nMAssay Description:Inhibitory activity against chicken liver dihydrofolate reductaseMore data for this Ligand-Target Pair