BDBM50544628 CHEMBL4638006

SMILES COc1cccc(C(=O)C2CCN(CCc3ccc(F)cc3)CC2)c1OC

InChI Key InChIKey=ALTAMTJSSZBUFX-UHFFFAOYSA-N

Data  6 KI  8 IC50  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50544628   

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544628(CHEMBL4638006)
Affinity DataKi:  0.520nMAssay Description:Displacement of [3H]-ketanserin from human HT2A receptor expressed in HEK293 cell membranes incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544628(CHEMBL4638006)
Affinity DataKi:  0.525nMAssay Description:Displacement of [3H]-ketanserin from human HT2A receptor expressed in HEK293 cell membranes incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544628(CHEMBL4638006)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A/mGlu2 receptor expressed in HEK293 cell membranes incubated for 2 hrs by scintillation counting meth...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544628(CHEMBL4638006)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A/mGlu2 receptor expressed in HEK293 cell membranes incubated for 2 hrs by scintillation counting meth...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544628(CHEMBL4638006)
Affinity DataKi:  8.70nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A/mGlu2 receptor expressed in HEK293 cell co-expressing Gqo5 membranes incubated for 2 hrs by scintill...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50544628(CHEMBL4638006)
Affinity DataKi:  8.70nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A/mGlu2 receptor expressed in HEK293 cell co-expressing Gqo5 membranes incubated for 2 hrs by scintill...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed