BDBM50065304 3-[1-(4-Hydroxy-phenyl)-meth-(Z)-ylidene]-1,3-dihydro-indol-2-one::CHEMBL313578
SMILES Oc1ccc(\C=C2/C(=O)Nc3ccccc23)cc1
InChI Key InChIKey=PLAOAGFXNCEZMZ-LCYFTJDESA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50065304
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of PLK1 (unknown origin) by FRET-based homogeneous assayMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of N-terminal GST-tagged human PLK4 (1 to 391 amino acids) expressed in Escherichia coli using TMB as substrate after 30 mins by indirect ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Her-2 receptor tyrosine kinase (HER-2 RTK)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Insulin-like growth factor I receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Epidermal growth factor receptor (EGF RTK).More data for this Ligand-Target Pair
Affinity DataIC50: 8.39E+3nMAssay Description:Test concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Platelet-derived growth factor receptor beta (PDGF RTK).More data for this Ligand-Target Pair