BDBM50187381 CHEMBL209324::N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-4-methylbenzenesulfonamide
SMILES COc1ccccc1N1CCN(CCCCNS(=O)(=O)c2ccc(C)cc2)CC1
InChI Key InChIKey=YMFRPPUSWRHMPF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50187381
Affinity DataKi: 1nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Displacement of [3H]prazosin from adrenergic alpha-1 receptor in rat cerebral cortex cellsMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [3H]RX 821002 from Adrenergic alpha-2a receptor in rat cerebral cortex cellsMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Binding affinity to 5HT7 receptor by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 53nMAssay Description:Binding affinity to 5HT2B receptor by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Binding affinity to 5HT transporter by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 490nMAssay Description:Binding affinity to 5HT2A receptor by radioligand binding assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Predix Pharmaceuticals
Curated by ChEMBL
Predix Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of hERG potassium channel in HEK293 cells by patch clamp assayMore data for this Ligand-Target Pair
Affinity DataEC50: 21nMAssay Description:Activity against 5HT1A receptor by Gi-[35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Predix Pharmaceuticals
Curated by ChEMBL
Predix Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human ERG channelMore data for this Ligand-Target Pair