BDBM206770 (S,S)- 2::US9492405, (S,S)-2

SMILES COc1cccc(C[C@H](C)NC[C@@H](O)c2cc(O)cc(O)c2)c1

InChI Key InChIKey=LGDWSGQDAWEKPG-UHFFFAOYSA-N

Data  2 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 206770   

TargetBeta-2 adrenergic receptor(Human)
Department Of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 206770BDBM206770( (S,S)- 2 | US9492405, (S,S)-2)
Affinity DataKd:  1.58E+4nMpH: 7.7Assay Description:HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2016
Entry Details
US Patent

TargetBeta-2 adrenergic receptor(Human)
Department Of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 206770BDBM206770( (S,S)- 2 | US9492405, (S,S)-2)
Affinity DataKi:  1.59E+4nM ΔG°:  -6.08kcal/molepH: 7.8 T: 2°CAssay Description:Beta1-AR binding was done on rat cortical membrane following a previously described procedure (Beer et al., Biochem. Pharmacol. 37: 1145-1151, 1988)....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2016
Entry Details
US Patent

TargetBeta-1 adrenergic receptor(Rat)
Department Of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 206770BDBM206770( (S,S)- 2 | US9492405, (S,S)-2)
Affinity DataKi: >1.00E+5nM ΔG°: >-5.07kcal/molepH: 7.8 T: 2°CAssay Description:Beta1-AR binding was done on rat cortical membrane following a previously described procedure (Beer et al., Biochem. Pharmacol. 37: 1145-1151, 1988)....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2016
Entry Details
US Patent