BDBM614819 A7-6-2::US20230271937, Example A7-6-2::US20230271937, Example A7-7-3::US20230271937, Example A7-7-4

SMILES NC(=O)CN1CC[C@H](CNc2ncnc(N(Cc3ccc(cc3)C(F)(F)F)C3CC3)c2F)C(F)(F)C1

InChI Key InChIKey=YCDPVBKMSVJQEA-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 614819   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614819(US20230271937, Example A7-6-2 | US20230271937, Exa...)
Affinity DataEC50:  4nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614819(US20230271937, Example A7-6-2 | US20230271937, Exa...)
Affinity DataEC50:  21nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614819(US20230271937, Example A7-6-2 | US20230271937, Exa...)
Affinity DataEC50:  170nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent