BDBM701953 ACV-2-127::US12129248, Compound ACV-44

SMILES COc1ccc(-c2ccc3nc(-c4ccco4)cc(C(=O)Nc4ccc(N5CCN(C)CC5)cc4)c3c2)cc1OC

InChI Key InChIKey=YAXMZBNHXLMRTD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 701953   

TargetChromobox protein homolog 7(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM701953(ACV-2-127 | US12129248, Compound ACV-44)
Affinity DataIC50: 0.0780nMAssay Description:The protocol for the CBX7 Fluorescence Polarization assay is as follows: A standard FP buffer (20 mM Tris, 250 mM NaCl, 0.01% w/v Tween20) at pH 8.0 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2025
Entry Details
US Patent