BDBM50395322 AMBROXOL

SMILES Nc1c(Br)cc(Br)cc1CN[C@H]1CC[C@H](O)CC1

InChI Key InChIKey=JBDGDEWWOUBZPM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50395322   

TargetLysosomal acid glucosylceramidase(Human)
Universitat Rovira I Virgili

Curated by ChEMBL
LigandPNGBDBM50395322(AMBROXOL)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of beta-glucocerebrosidase in human fibroblast lysate using 4-methylumbelliferyl beta-D-glycopyranoside as substrate by fluorimetric analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Universitat Rovira I Virgili

Curated by ChEMBL
LigandPNGBDBM50395322(AMBROXOL)
Affinity DataEC50:  2.94E+4nMAssay Description:Positive allosteric modulation of GCase in human Fibroblast cells using GBA1-FQ2 as substrate preincubated for 24 hrs followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed