BDBM50378913 APG2449::Apg 2449::Apg-2449

SMILES Cc1cc(Nc2ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(C)C)n2)c(OC(C)C)cc1C1=CCN(C2CCOCC2)CC1

InChI Key InChIKey=YWPHBSHEGTZPNS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50378913   

TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378913BDBM50378913(Apg 2449 | Apg-2449 | APG2449)
Affinity DataIC50: 0.810nMAssay Description:Inhibition of VEGFR3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378913BDBM50378913(Apg 2449 | Apg-2449 | APG2449)
Affinity DataIC50: 1.60nMAssay Description:In vitro cell based assay for measuring the IC50 values of osteoblast resorption.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMed
TargetFocal adhesion kinase 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378913BDBM50378913(Apg 2449 | Apg-2449 | APG2449)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of TACE by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMed