BDBM50546247 AR-11324 FREE BASE::AR-13324::Netarsudil::US11485707, Example Reference compound 1
SMILES Cc1ccc(C(=O)OCc2ccc(cc2)[C@@H](CN)C(=O)Nc2ccc3cnccc3c2)c(C)c1
InChI Key InChIKey=OURRXQUGYQRVML-AREMUKBSSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 25 hits for monomerid = 50546247
Affinity DataKi: 1nMAssay Description:Inhibition of recombinant human GST-tagged ROCK2 catalytic domain expressed in baculovirus expression system by Kinase-Glo luminescent kinase assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of Rock2 (unknown origin) by Kinase Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of Rock1 (unknown origin) by Kinase Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of recombinant human GST-tagged ROCK1 catalytic domain expressed in baculovirus expression system by Kinase-Glo luminescent kinase assayMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of Rock2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Inhibition of human ROCK2 by Kinase-Glo luminescent assayMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Table 2: ROCK-I(h) kinase assays were conducted using the KinaseProfiler™ service of Eurofins Pharma Discovery Services UK Limited. ROCK-I(h) was inc...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Table 2: ROCK-II(h) kinase assays were conducted using the KinaseProfiler™ service of Eurofins Pharma Discovery Services UK Limited. ROCK-II(h) was i...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Table 2: ROCK-I(h) kinase assays were conducted using the KinaseProfiler™ service of Eurofins Pharma Discovery Services UK Limited. ROCK-I(h) was inc...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Table 2: ROCK-I(h) kinase assays were conducted using the KinaseProfiler™ service of Eurofins Pharma Discovery Services UK Limited. ROCK-I(h) was inc...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Table 2: ROCK-I(h) kinase assays were conducted using the KinaseProfiler™ service of Eurofins Pharma Discovery Services UK Limited. ROCK-I(h) was inc...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Table 2: ROCK-I(h) kinase assays were conducted using the KinaseProfiler™ service of Eurofins Pharma Discovery Services UK Limited. ROCK-I(h) was inc...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Table 2: ROCK-I(h) kinase assays were conducted using the KinaseProfiler™ service of Eurofins Pharma Discovery Services UK Limited. ROCK-I(h) was inc...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Table 2: ROCK-I(h) kinase assays were conducted using the KinaseProfiler™ service of Eurofins Pharma Discovery Services UK Limited. ROCK-I(h) was inc...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Table 2: ROCK-I(h) kinase assays were conducted using the KinaseProfiler™ service of Eurofins Pharma Discovery Services UK Limited. ROCK-I(h) was inc...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Table 2: ROCK-I(h) kinase assays were conducted using the KinaseProfiler™ service of Eurofins Pharma Discovery Services UK Limited. ROCK-I(h) was inc...More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Table 2: ROCK-I(h) kinase assays were conducted using the KinaseProfiler™ service of Eurofins Pharma Discovery Services UK Limited. ROCK-I(h) was inc...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Table 2: ROCK-I(h) kinase assays were conducted using the KinaseProfiler™ service of Eurofins Pharma Discovery Services UK Limited. ROCK-I(h) was inc...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Table 2: ROCK-I(h) kinase assays were conducted using the KinaseProfiler™ service of Eurofins Pharma Discovery Services UK Limited. ROCK-I(h) was inc...More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Table 2: ROCK-I(h) kinase assays were conducted using the KinaseProfiler™ service of Eurofins Pharma Discovery Services UK Limited. ROCK-I(h) was inc...More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Table 2: ROCK-I(h) kinase assays were conducted using the KinaseProfiler™ service of Eurofins Pharma Discovery Services UK Limited. ROCK-I(h) was inc...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Table 2: ROCK-I(h) kinase assays were conducted using the KinaseProfiler™ service of Eurofins Pharma Discovery Services UK Limited. ROCK-I(h) was inc...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Table 2: ROCK-II(h) kinase assays were conducted using the KinaseProfiler™ service of Eurofins Pharma Discovery Services UK Limited. ROCK-II(h) was i...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Table 2: ROCK-II(h) kinase assays were conducted using the KinaseProfiler™ service of Eurofins Pharma Discovery Services UK Limited. ROCK-II(h) was i...More data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Table 2: ROCK-I(h) kinase assays were conducted using the KinaseProfiler™ service of Eurofins Pharma Discovery Services UK Limited. ROCK-I(h) was inc...More data for this Ligand-Target Pair