BDBM50049390 1-Hydroxy-2,3-dimethoxy-10-methyl-10H-acridin-9-one::1-hydroxy-2,3-dimethoxy-10-methyl-9-acridone::1-hydroxy-2,3-dimethoxy-N-methylacridone::ARBORININE::CHEMBL349609

SMILES COc1cc2n(C)c3ccccc3c(=O)c2c(O)c1OC

InChI Key InChIKey=ATBZZQPALSPNMF-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50049390   

TargetLysine-specific histone demethylase 1A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50049390(CHEMBL349609 | 1-hydroxy-2,3-dimethoxy-10-methyl-9...)
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant LSD1 (unknown origin) incubated for 1 hr by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetAdenosine receptor A2a(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50049390(CHEMBL349609 | 1-hydroxy-2,3-dimethoxy-10-methyl-9...)
Affinity DataKi:  6.47E+3nMAssay Description:Affinity at Adenosine A2A receptor in rat striatal membranes by [3H]- CGS 21680 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50049390(CHEMBL349609 | 1-hydroxy-2,3-dimethoxy-10-methyl-9...)
Affinity DataKi:  1.27E+4nMAssay Description:Displacement of specific [3H]PIA binding from adenosine A1 receptor in rat brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed