BDBM50649858 Derazantinib::Arq-087::ARQ 087::ARQ087

SMILES COCCNCCc1cccc(Nc2ncc3c(n2)-c2ccccc2[C@H](c2ccccc2F)C3)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50649858   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50649858(Derazantinib | Arq-087 | ARQ 087 | ARQ087)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of CSF1R (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 3(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50649858(Derazantinib | Arq-087 | ARQ 087 | ARQ087)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of recombinant N-terminal GST tagged FGFR3 (436 to 806 residues) (unknown origin) expressed in Sf21 cells using biotinylated PYK2 peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50649858(Derazantinib | Arq-087 | ARQ 087 | ARQ087)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of recombinant N-terminal GST tagged FGFR2 (399 to 821 residues) (unknown origin) expressed in Sf21 cells using biotinylated PYK2 peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50649858(Derazantinib | Arq-087 | ARQ 087 | ARQ087)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of recombinant N-terminal GST tagged FGFR1 (398 to 822 residues) (unknown origin) expressed in Sf21 cells using biotinylated PYK2 peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed