BDBM50640216 Pf-07284892::ARRY-558

SMILES Nc1nccc(Sc2cnc(N3CCC4(CC3)Cc3ccccc3[C@H]4N)nn2)c1Cl

InChI Key

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50640216   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50640216(Pf-07284892 | ARRY-558)
Affinity DataIC50: 21nMAssay Description:Inhibition of C-terminal 6His-tagged full length SHP2 (2 to 527 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)