BDBM50502477 ASB-183::ASB183::Afuresertib::GSK-2110183C::GSK2110183::GSK2110183C::Gsk-2110183

SMILES [H][C@@](CN)(Cc1cccc(F)c1)NC(=O)c1cc(c(Cl)s1)-c1c(Cl)cnn1C

InChI Key InChIKey=AFJRDFWMXUECEW-LBPRGKRZSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50502477   

TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Hangzhou Institute of Innovative Medicine

Curated by ChEMBL
LigandPNGBDBM50502477(ASB-183 | ASB183 | Afuresertib | GSK-2110183C | GS...)
Affinity DataKi:  0.0800nMAssay Description:Inhibition of Akt1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))TBA
LigandPNGBDBM50502477(ASB-183 | ASB183 | Afuresertib | GSK-2110183C | GS...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of acetylcholinesterase (AChE) activityMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))TBA
LigandPNGBDBM50502477(ASB-183 | ASB183 | Afuresertib | GSK-2110183C | GS...)
Affinity DataIC50:  2nMAssay Description:Inhibition of choline acetyltransferase (ChAT) activityMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Hangzhou Institute of Innovative Medicine

Curated by ChEMBL
LigandPNGBDBM50502477(ASB-183 | ASB183 | Afuresertib | GSK-2110183C | GS...)
Affinity DataIC50:  17nMAssay Description:Inhibition of Akt1 (unknown origin) expressed in Escherichia coli using peptide as substrate incubated for 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Hangzhou Institute of Innovative Medicine

Curated by ChEMBL
LigandPNGBDBM50502477(ASB-183 | ASB183 | Afuresertib | GSK-2110183C | GS...)
Affinity DataIC50:  0.0800nMAssay Description:Inhibition of acetylcholinesterase (AChE) activityMore data for this Ligand-Target Pair
In DepthDetails PubMed