BDBM50267626 AZ-11548415::AZD-1080

SMILES Oc1[nH]c2ccc(cc2c1-c1ccc(CN2CCOCC2)cn1)C#N

InChI Key InChIKey=BLTVBQXJFVRPFK-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50267626   

TargetGlycogen synthase kinase-3 beta(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50267626(AZ-11548415 | AZD-1080)
Affinity DataIC50: 31nMAssay Description:Inhibition of GSK3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50267626(AZ-11548415 | AZD-1080)
Affinity DataKi:  31nMAssay Description:Inhibition of recombinant full length human GSK3beta expressed in Sf21 insect cells using biotinylated-AAEELDSRAGS(PO3H2)PQL peptide as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed