BDBM50635713 Azd-9574::AZD9574::US20250346573, Compound AZD9574

SMILES CNC(=O)c1ccc(N2CCN(Cc3ccc4nc(C)c(=O)[nH]c4c3F)CC2)c(F)n1

InChI Key

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50635713   

TargetPoly [ADP-ribose] polymerase 1(Human)
CHENGDU EASTON BIOPHARMACEUTICALS CO., LTD.

US Patent
LigandChemical structure of BindingDB Monomer ID 50635713BDBM50635713(Azd-9574 | AZD9574 | US20250346573, Compound AZD95...)
Affinity DataIC50: 0.602nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent
PDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
CHENGDU EASTON BIOPHARMACEUTICALS CO., LTD.

US Patent
LigandChemical structure of BindingDB Monomer ID 50635713BDBM50635713(Azd-9574 | AZD9574 | US20250346573, Compound AZD95...)
Affinity DataIC50: 5nMAssay Description:Inhibition of PARP1 (unknown origin) expressed in Escherichia coli BL21 incubated for 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 2(Human)
CHENGDU EASTON BIOPHARMACEUTICALS CO., LTD.

US Patent
LigandChemical structure of BindingDB Monomer ID 50635713BDBM50635713(Azd-9574 | AZD9574 | US20250346573, Compound AZD95...)
Affinity DataIC50: 3.48E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent