BDBM50088366 Ajmaline

SMILES CCC1C2CC3C4N(C)c5ccccc5C44CC(C2[C@H]4O)N3C1O

InChI Key InChIKey=CJDRUOGAGYHKKD-FUIWMBJSSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50088366   

TargetSodium channel protein type 1/10/11/2/3/4/5/7/8/9 subunit alpha(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50088366(Ajmaline)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibition of Na channel (species unknown)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50088366(Ajmaline)
Affinity DataIC50:  7.10E+4nMAssay Description:Inhibition of voltage-gated L-type Ca channel (species unknown)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50088366(Ajmaline)
Affinity DataIC50: >6.12E+5nMAssay Description:Inhibition of HIV1 RTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50088366(Ajmaline)
Affinity DataIC50:  7.08E+4nMAssay Description:Inhibition of L-type calcium channel measured using whole-cell patch clamp in rat ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50088366(Ajmaline)
Affinity DataIC50:  1.04E+3nMAssay Description:Inhibition of hERG K channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed