BDBM100310 US9695200, 60

SMILES COc1cc(/C=C(\C#N)C(N)=O)cc(-c2cnc3[nH]cc(-c4ccnc(OC)c4)c3c2)c1

InChI Key InChIKey=OEFSVAYBAKZLHC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 100310   

TargetTyrosine-protein kinase ITK/TSK(Human)
Confluence Life Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 100310BDBM100310(US9695200, 60)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is based on the binding of a proprietary, Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor (kinase tracer-236) to the ITK express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent

Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1(Human)
Confluence Life Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 100310BDBM100310(US9695200, 60)
Affinity DataIC50: 5.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2018
Entry Details
US Patent