BDBM10070 ({2-[(2R,15S)-15-methyl-5,14-dioxotetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-1(17),6-dien-2-yl]ethyl}sulfanyl)carbonitrile::3,17-Dioxo-19-[(thiocyanato)methyl]androsta-4,9(11)-diene::RU54115 Analog 43

SMILES C[C@]12CC=C3C(CCC4=CC(=O)CC[C@]34CCSC#N)C1CCC2=O

InChI Key InChIKey=RCUYUXXIFXLVMF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10070   

TargetAromatase(Human)
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10070(3,17-Dioxo-19-[(thiocyanato)methyl]androsta-4,9(11...)
Affinity DataIC50: 1.00E+3nMAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed