BDBM10071 (2R,15S)-2-[2,2-bis(methylsulfanyl)ethyl]-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-1(17),6-diene-5,14-dione::3,17-Dioxo-19-[1,1-bis(methylthio)methyl]androsta-4,9(11)-diene::RU54115 Analog 50

SMILES CSC(C[C@]12CCC(=O)C=C1CCC1C3CCC(=O)[C@@]3(C)CC=C21)SC

InChI Key InChIKey=IOCUBCQIWVMCHZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10071   

TargetAromatase(Human)
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10071(3,17-Dioxo-19-[1,1-bis(methylthio)methyl]androsta-...)
Affinity DataIC50: 1.00E+3nMAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed