BDBM100997 US8507479, 70

SMILES COCCOc1cnc(C(=O)Nc2cccc([C@]3(C)CCSC(N)=N3)c2)cn1

InChI Key InChIKey=RJVJNKJJGQFNQK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 100997   

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 100997BDBM100997(US8507479, 70)
Affinity DataIC50: 90nMAssay Description:Beta-Secretase inhibition assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2013
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 100997BDBM100997(US8507479, 70)
Affinity DataIC50: 90nMpH: 7.0Assay Description:Inhibition assay using human BACE-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
US Patent