BDBM101014 US8507479, 136

SMILES C[C@@]1(c2cc(NC(=O)c3cnc(-c4ccco4)cn3)ccc2F)CCSC(N)=N1

InChI Key InChIKey=DDUHVQZYSCUFKU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 101014   

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 101014BDBM101014(US8507479, 136)
Affinity DataIC50: 110nMAssay Description:Beta-Secretase inhibition assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2013
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 101014BDBM101014(US8507479, 136)
Affinity DataIC50: 110nMpH: 7.0Assay Description:Inhibition assay using human BACE-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
US Patent