BDBM10112 (3Z)-5-fluoro-3-[(3-methoxy-1H-pyrrol-2-yl)methylidene]-4-{2-[(2S)-pyrrolidin-2-yl]ethynyl}-2,3-dihydro-1H-indol-2-one::4-alkynyl oxindole 7r
SMILES COc1cc[nH]c1\C=C1/C(=O)Nc2ccc(F)c(C#C[C@@H]3CCCN3)c12
InChI Key InChIKey=NOCXREGHIRXAHY-PBBNAPBQSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 10112
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK2 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair