BDBM101438 US8530652, 47::US8530670, 15::US8530670, 2

SMILES Fc1cccc(C2N(C(=O)CC2=O)c2ccc3nc[nH]c3c2)c1F

InChI Key InChIKey=LJIAMQXFSCERQG-UHFFFAOYSA-N

Data  2 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 101438   

TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

US Patent
LigandPNGBDBM101438(US8530670, 15 | US8530670, 2 | US8530652, 47)
Affinity DataKi:  18.8nM ΔG°:  -10.7kcal/mole IC50: 85.8nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrate. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2013
Entry Details
US Patent

TargetSerine/threonine-protein kinase PAK 4(Human)
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101438(US8530670, 15 | US8530670, 2 | US8530652, 47)
Affinity DataKi:  370nM EC50:  401nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2013
Entry Details
US Patent