BDBM101828 US9695160, 41::US9796707, Compound 41

SMILES CN1CCN(c2ccc(C(F)(F)F)cc2NC(=O)c2nc(-c3ccccc3)c[nH]2)CC1

InChI Key InChIKey=XHFFHDPLDWFOLQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 101828   

TargetSRSF protein kinase 1(Human)
The University of Nottingham

US Patent
LigandChemical structure of BindingDB Monomer ID 101828BDBM101828(US9695160, 41 | US9796707, Compound 41)
Affinity DataIC50: 493nMT: 2°CAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetSRSF protein kinase 1(Human)
The University of Nottingham

US Patent
LigandChemical structure of BindingDB Monomer ID 101828BDBM101828(US9695160, 41 | US9796707, Compound 41)
Affinity DataIC50: 493nMAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent