BDBM102173 US8530648, 97
SMILES O=C1CCCC2(CCN(CC2)c2cnc3ccccc3n2)N1Cc1c[nH]c2ccccc12
InChI Key InChIKey=OBJJCTFQGWCXGH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 102173
Affinity DataKi: 47nMpH: 7.4Assay Description:FLIPR assay using orexin receptor.More data for this Ligand-Target Pair
Affinity DataKi: 69nMAssay Description:Antagonist activity at human OX2 receptor expressed in HEK cells assessed as inhibition of orexin A-induced Ca2+ accumulation after 1 hr by Fluo-4-AM...More data for this Ligand-Target Pair
Affinity DataKi: 236nMpH: 7.4Assay Description:FLIPR assay using orexin receptor.More data for this Ligand-Target Pair
Affinity DataKi: 275nMAssay Description:Antagonist activity at human OX1 receptor expressed in CHO cells assessed as inhibition of orexin A-induced Ca2+ accumulation after 1 hr by Fluo-4-AM...More data for this Ligand-Target Pair
Affinity DataKd: 205nMpH: 7.5Assay Description:Radioligand binding assay using orexin receptor.More data for this Ligand-Target Pair
Affinity DataKd: 196nMpH: 7.5Assay Description:Radioligand binding assay using orexin receptor.More data for this Ligand-Target Pair