BDBM10231 5-chloro-2-ethyl-7-methyl-13-[(pyrimidin-5-ylsulfanyl)methyl]-2,4,9,15-tetraazatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-10-one::8-heteroarylthiomethyldipyridodiazepinone deriv. 13
SMILES CCN1c2nc(Cl)cc(C)c2NC(=O)c2cc(CSc3cncnc3)cnc12
InChI Key InChIKey=UWBOVNUZRAIRLM-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 10231
TargetGag-Pol polyprotein [600-1027,K702N,Y780C]/[600-1155,K702N,Y780C](Human immunodeficiency virus type 1)
Boehringer Ingelheim (Canada)
Boehringer Ingelheim (Canada)
Affinity DataIC50: 5.00E+3nMpH: 7.4 T: 37°CAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim (Canada)
Boehringer Ingelheim (Canada)
Affinity DataIC50: 26nMpH: 7.4 T: 37°CAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair