BDBM10254 Isoquinoline-1,3,4-trione 6a::N-(1,3,4-Trioxo-1,2,3,4-tetrahydro-isoquinolin-5-yl)-benzamide::N-(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)benzamide

SMILES O=C(Nc1cccc2C(=O)NC(=O)C(=O)c12)c1ccccc1

InChI Key InChIKey=WXTWECMQVXQLNG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10254   

TargetCaspase-3(Homo sapiens (Human))
Shanghai Institutes For Biological Sciences

LigandPNGBDBM10254(Isoquinoline-1,3,4-trione 6a | N-(1,3,4-Trioxo-1,2...)
Affinity DataIC50:  110nMpH: 7.5 T: 2°CAssay Description:The rate of chromogenic substrate hydrolysis was monitored by the change of absorbance at 405 nm for 3 min. Compounds were tested in duplicate. The I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed