BDBM102566 US8536172, I-15

SMILES CN(C)S(=O)(=O)N[C@H]1CC[C@@H](CC1)Nc1nccc(n1)-n1ccc2c(cccc12)N1CCC(CC1)S(C)(=O)=O

InChI Key InChIKey=XTEAWRJATFUZSV-MXVIHJGJSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 102566   

TargetMitogen-activated protein kinase 8(Human)
Roche Palo Alto

US Patent
LigandPNGBDBM102566(US8536172, I-15)
Affinity DataIC50:  20.8nMpH: 7.5Assay Description:JNK activity was measured by phosphorylation of GST-ATF2 (19-96) with [gamma-33P] ATP.More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetMitogen-activated protein kinase 8(Human)
Roche Palo Alto

US Patent
LigandPNGBDBM102566(US8536172, I-15)
Affinity DataIC50:  3.60nMpH: 7.5Assay Description:JNK activity was measured by phosphorylation of GST-ATF2 (19-96) with [gamma-33P] ATP.More data for this Ligand-Target Pair
In DepthDetails US Patent