BDBM102763 US8541572, 1509

SMILES COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3ccc(nc3)N3CCCCC3)C(=O)c2c1

InChI Key InChIKey=LZGXRCVRZKUPAC-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 102763   

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102763(US8541572, 1509)
Affinity DataKi:  0.190nM IC50: 514nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
US Patent