BDBM102898 US8541572, 2292

SMILES COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3ccc(nc3)-c3cn[nH]c3)C(=O)c2c1

InChI Key InChIKey=UFDVOXPVFWMEPY-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 102898   

TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102898(US8541572, 2292)
Affinity DataKi:  0.190nM IC50: 372nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
US Patent