BDBM103366 US8552202, Compound 15

SMILES C[C@H]1CC[C@H]([C@H](NC(=O)c2cccc(-n3ccnc3)c2)C(=O)N2C[C@H](F)[C@H]3OCC(=O)[C@H]32)CC1

InChI Key InChIKey=GXCSFFZWKWHFDR-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 103366   

TargetCathepsin S(Human)
Amura Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 103366BDBM103366(US8552202, Compound 15)
Affinity DataKi:  15nMAssay Description:In vitro inhibition assay using cathepsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2013
Entry Details
US Patent

TargetCathepsin L2(Human)
Amura Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 103366BDBM103366(US8552202, Compound 15)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro inhibition assay using cathepsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2013
Entry Details
US Patent

TargetCathepsin K(Human)
Amura Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 103366BDBM103366(US8552202, Compound 15)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro inhibition assay using cathepsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2013
Entry Details
US Patent

TargetProcathepsin L(Human)
Amura Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 103366BDBM103366(US8552202, Compound 15)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro inhibition assay using cathepsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2013
Entry Details
US Patent

TargetCathepsin B(Human)
Amura Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 103366BDBM103366(US8552202, Compound 15)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro inhibition assay using cathepsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2013
Entry Details
US Patent