BDBM103465 US8552004, 1.01

SMILES C[C@@H]1COCCN1c1cc(C[S@](C)(=N)=O)nc(n1)-c1ccnc2[nH]ccc12

InChI Key InChIKey=FEFZJKWFEQKDHO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 103465   

TargetSerine/threonine-protein kinase ATR(Human)
Astrazeneca

US Patent
LigandPNGBDBM103465(US8552004, 1.01)
Affinity DataIC50: 34.0nMpH: 7.4 T: 2°CAssay Description:ATR for use in the in vitro enzyme assay was obtained from HeLa nuclear extract (CIL Biotech, Mons, Belgium) by immunoprecipitation with rabbit polyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2014
Entry Details
US Patent

TargetSerine/threonine-protein kinase ATR(Human)
Astrazeneca

US Patent
LigandPNGBDBM103465(US8552004, 1.01)
Affinity DataIC50: 581nMAssay Description:ATM and ATR have distinct and overlapping responses to DNA damage. They must participate together and responses must be co-ordinated. Both pathways...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2014
Entry Details
US Patent