BDBM103649 US8563553, 74

SMILES CCS(=O)(=O)Nc1cc(Cl)cc(-c2[nH]c(nc2-c2ccnc(NC[C@H](C)NC(=O)OC)n2)C2CC2)c1F

InChI Key InChIKey=PWMKVDVQZIUERF-LBPRGKRZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 103649   

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Novartis

US Patent
LigandPNGBDBM103649(US8563553, 74)
Affinity DataIC50:  0.240nMpH: 7.5Assay Description:Raf/Mek amplified luminescence proximity homogeneous assay.More data for this Ligand-Target Pair
In DepthDetails US Patent