BDBM103853 US9695165, 36

SMILES C=CC(=O)N1CCOc2ccc(-c3ncc4cc(-c5c(Cl)c(OC)cc(OC)c5Cl)c(OC)cc4n3)cc21

InChI Key InChIKey=ISTIAELPJMRLGH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 103853   

TargetFibroblast growth factor receptor 4(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 103853BDBM103853(US9695165, 36)
Affinity DataIC50: 55nMpH: 7.5 T: 2°CAssay Description:In each well of a 384-well plate, 0.5 ng/ul of wild type FGFR-4 (Carna Biosciences, Inc.) was incubated in a total of 12.5 ul of buffer (100 mM HEPES...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent