BDBM103858 US9695165, 41

SMILES C=CC(=O)Nc1cc(F)c(F)c(-c2cc3c(cn2)cc(-c2c(Cl)c(OC)cc(OC)c2Cl)c(=O)n3CC)c1

InChI Key InChIKey=XISVWZUUDMYARH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 103858   

TargetFibroblast growth factor receptor 4(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 103858BDBM103858(US9695165, 41)
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:In each well of a 384-well plate, 0.5 ng/ul of wild type FGFR-4 (Carna Biosciences, Inc.) was incubated in a total of 12.5 ul of buffer (100 mM HEPES...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent