BDBM103873 US9695165, 56

SMILES C=CC(=O)N1CCOc2ccc(-c3cc4c(cn3)nc(-c3c(Cl)c(OC)cc(OC)c3Cl)c(=O)n4C3CCCC3)cc21

InChI Key InChIKey=STFGDNAMWSFVRE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 103873   

TargetFibroblast growth factor receptor 4(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 103873BDBM103873(US9695165, 56)
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:In each well of a 384-well plate, 0.5 ng/ul of wild type FGFR-4 (Carna Biosciences, Inc.) was incubated in a total of 12.5 ul of buffer (100 mM HEPES...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent