BDBM105071 US8569281, 39

SMILES C1CCC(C1)n1cc(cn1)-c1n[nH]c2ccnc(OC3CCOCC3)c12

InChI Key InChIKey=REWYYRDPMFBIQK-UHFFFAOYSA-N

Data  1 KI  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 105071   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Lifearc

Curated by ChEMBL

LigandBDBM105071(US8569281, 39)Copy SMILESCopy InChI

Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human GST-tagged LRRK2 G2019S mutant catalytic domain (970 to 2527 residues) expressed in baculovirus expression system by ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/19/2021
Entry Details Article
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TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Lifearc

Curated by ChEMBL

LigandBDBM105071(US8569281, 39)Copy SMILESCopy InChI

Affinity DataKi:  6nMAssay Description:This assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining Kiapp, IC50 or percent inhibition values.More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/24/2014
Entry Details
Copy BDB DOIUS Patent

Copy reaction URL