BDBM105100 US8569281, 110

SMILES C1CCN(C1)c1cc(ccn1)-c1n[nH]c2ccnc(OC3CCOCC3)c12

InChI Key InChIKey=AOEBFKZJGQPEOC-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 105100   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandPNGBDBM105100(US8569281, 110)
Affinity DataIC50: 3nMAssay Description:Inhibition of full length wild-type LRRK2 (unknown origin) using biotinylated ezrin/radaxin/meosin peptide as substrate measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2019
Entry Details Article
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Charles River Discovery Research Services

Curated by ChEMBL
LigandPNGBDBM105100(US8569281, 110)
Affinity DataKi:  3nMAssay Description:This assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining Kiapp, IC50 or percent inhibition values.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
US Patent