BDBM10651 2-purine deriv. 17::4-(6-{[(4-methoxyphenyl)methyl]amino}-9-(propan-2-yl)-9H-purin-2-yl)benzaldehyde

SMILES COc1ccc(CNc2nc(nc3n(cnc23)C(C)C)-c2ccc(C=O)cc2)cc1

InChI Key InChIKey=GQOCHUAIPCTWKU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 10651   

LigandPNGBDBM10651(4-(6-{[(4-methoxyphenyl)methyl]amino}-9-(propan-2-...)
Affinity DataIC50: 1.30E+3nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Institut Curie

LigandPNGBDBM10651(4-(6-{[(4-methoxyphenyl)methyl]amino}-9-(propan-2-...)
Affinity DataIC50: 1.50E+3nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Rat)
Institut Curie

LigandPNGBDBM10651(4-(6-{[(4-methoxyphenyl)methyl]amino}-9-(propan-2-...)
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2006
Entry Details Article
PubMed