BDBM106721 US8586620, 111

SMILES CN1CCC(c2c[nH]c3ccc(N=C(N)c4ccco4)cc23)C1

InChI Key InChIKey=HNZXYYYKZVJWFM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 106721   

Target5-hydroxytryptamine 1D receptor(Bovine)
Neuraxon

US Patent
LigandChemical structure of BindingDB Monomer ID 106721BDBM106721(US8586620, 111)
Affinity DataIC50: 560nMAssay Description:5-HT1D binding assays (agonist radioligand)were performed using bovine caudate membranes according to the methods of Heuring and Peroutka (J. Neurosc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2014
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1B(Rat)
Neuraxon

US Patent
LigandChemical structure of BindingDB Monomer ID 106721BDBM106721(US8586620, 111)
Affinity DataIC50: 1.10E+3nMAssay Description:5-HT1D binding assays (agonist radioligand)were performed using bovine caudate membranes according to the methods of Heuring and Peroutka (J. Neurosc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2014
Entry Details
US Patent

TargetNitric oxide synthase, brain(Human)
Neuraxon

US Patent
LigandChemical structure of BindingDB Monomer ID 106721BDBM106721(US8586620, 111)
Affinity DataIC50: 1.24E+3nMAssay Description:Enzyme assay using recombinant human inducible NOS (iNOS), human endothelial constitutive NOS (eNOS) or human neuronal constitutive NOS (nNOS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2014
Entry Details
US Patent

TargetNitric oxide synthase, endothelial(Human)
Neuraxon

US Patent
LigandChemical structure of BindingDB Monomer ID 106721BDBM106721(US8586620, 111)
Affinity DataIC50: 3.38E+4nMAssay Description:Enzyme assay using recombinant human inducible NOS (iNOS), human endothelial constitutive NOS (eNOS) or human neuronal constitutive NOS (nNOS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2014
Entry Details
US Patent