BDBM10698 3-{[methyl(7-{[(2Z)-2-(1-naphthylmethylene)-3-oxo-2,3-dihydro-1-benzofuran-6-yl]oxy}heptyl)amino]methyl}phenyl methylcarbamate::3-{[methyl(7-{[(2Z)-2-(naphthalen-1-ylmethylidene)-3-oxo-2,3-dihydro-1-benzofuran-6-yl]oxy}heptyl)amino]methyl}phenyl N-methylcarbamate::CHEMBL364545::Xanthostigmine deriv. 10b

SMILES CNC(=O)Oc1cccc(CN(C)CCCCCCCOc2ccc3C(=O)C(Oc3c2)=Cc2cccc3ccccc23)c1

InChI Key InChIKey=WNFYHXIHRPVKKQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 10698   

TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10698(3-{[methyl(7-{[(2Z)-2-(1-naphthylmethylene)-3-oxo-...)
Affinity DataIC50:  2.76nMpH: 8.0 T: 37°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10698(3-{[methyl(7-{[(2Z)-2-(1-naphthylmethylene)-3-oxo-...)
Affinity DataIC50:  2.76E+3nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10698(3-{[methyl(7-{[(2Z)-2-(1-naphthylmethylene)-3-oxo-...)
Affinity DataIC50:  2.09nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCholinesterase(Human)
University of Bologna

LigandPNGBDBM10698(3-{[methyl(7-{[(2Z)-2-(1-naphthylmethylene)-3-oxo-...)
Affinity DataIC50:  40.2nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed