BDBM10722 3-{[methyl({3-[(9-oxo-9H-xanthen-3-yl)oxy]propyl})amino]methyl}phenyl N-[6-(morpholin-4-yl)hexyl]carbamate::aminoalkoxyaryl deriv. 15a

SMILES CN(CCCOc1ccc2c(c1)oc1ccccc1c2=O)Cc1cccc(OC(=O)NCCCCCCN2CCOCC2)c1

InChI Key InChIKey=HZBWHMWKDXVMMX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 10722   

TargetCholinesterase(Human)
University of Bologna

LigandPNGBDBM10722(3-{[methyl({3-[(9-oxo-9H-xanthen-3-yl)oxy]propyl})...)
Affinity DataIC50: 7.5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10722(3-{[methyl({3-[(9-oxo-9H-xanthen-3-yl)oxy]propyl})...)
Affinity DataIC50: 21.1nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10722(3-{[methyl({3-[(9-oxo-9H-xanthen-3-yl)oxy]propyl})...)
Affinity DataIC50: 21.1nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed