BDBM10754 3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-5-yl N,N-dimethylcarbamate; methanesulfonic acid::Aminoindan deriv. 18a::Aminoindan deriv. 18a.Mesylate::N-propargylaminoindan 18a.Mesylate

SMILES CN(C)C(=O)Oc1ccc2CCC(NCC#C)c2c1

InChI Key InChIKey=HLSVSCQFGAPXKJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 10754   

TargetCarboxylic ester hydrolase(Horse)
Teva Pharmaceutical Industries

LigandChemical structure of BindingDB Monomer ID 10754BDBM10754(3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-5-yl ...)
Affinity DataIC50: 2.07E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Teva Pharmaceutical Industries

LigandChemical structure of BindingDB Monomer ID 10754BDBM10754(3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-5-yl ...)
Affinity DataIC50: 5.30E+5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Teva Pharmaceutical Industries

LigandChemical structure of BindingDB Monomer ID 10754BDBM10754(3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-5-yl ...)
Affinity DataIC50: 7.50E+5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed