BDBM10766 (3R)-3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-5-yl N-butyl-N-methylcarbamate::Aminoindan deriv. (R)18i::N-propargylaminoindan (R)18i

SMILES CCCCN(C)C(=O)Oc1ccc2CC[C@@H](NCC#C)c2c1

InChI Key InChIKey=PBBZQCRCUHDOBK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 10766   

TargetAcetylcholinesterase(Human)
Teva Pharmaceutical Industries

LigandChemical structure of BindingDB Monomer ID 10766BDBM10766(N-propargylaminoindan (R)18i | (3R)-3-(prop-2-yn-1...)
Affinity DataIC50: 1.16E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Teva Pharmaceutical Industries

LigandChemical structure of BindingDB Monomer ID 10766BDBM10766(N-propargylaminoindan (R)18i | (3R)-3-(prop-2-yn-1...)
Affinity DataIC50: 1.50E+5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Teva Pharmaceutical Industries

LigandChemical structure of BindingDB Monomer ID 10766BDBM10766(N-propargylaminoindan (R)18i | (3R)-3-(prop-2-yn-1...)
Affinity DataIC50: 2.20E+5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed